
Ref: GHK-CU-50MG
Verified Vanguard Lab Batch COA
Certificate of Analysis โ GHK-CU-50MG
Third-party HPLC purity chromatogram & mass spec lab report.
Matrix Biology Research
GHK-Cu
Copper Tripeptide-1 Research Compound
GHK-Cu is a naturally occurring copper-binding peptide complex made from the amino acid sequence glycyl-L-histidyl-L-lysine. It has been widely studied in laboratory and cosmetic-science research for its role in copper transport, extracellular matrix signaling, collagen-related pathways, and cellular signaling pathways observed in controlled laboratory models.
$89.00 USD
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Strictly for laboratory research use only. Not for human or animal consumption.

Ref: GHK-CU-50MG
Verified Vanguard Lab Batch COA
Certificate of Analysis โ GHK-CU-50MG
Third-party HPLC purity chromatogram & mass spec lab report.
01
What Is GHK-Cu?
GHK-Cu is a naturally occurring tripeptide first isolated from human plasma in 1973. It has a high affinity for copper ions (Cu2+) and spontaneously forms a complex known as GHK-Cu. This complex acts as a vital signaling molecule in biological systems, particularly involved in tissue remodeling and cellular protection.
In laboratory research, GHK-Cu is studied for its ability to modulate various biological pathways, including the upregulation of collagen and glycosaminoglycan synthesis. Its unique structure allows it to serve as a carrier for copper into cells, facilitating enzymatic processes essential for extracellular matrix maintenance.
02
Research Pathways & Mechanisms
Collagen & ECM Pathways
Studies the stimulation of glycosaminoglycans and collagen types I and III.
Simple explanation: Researching how GHK-Cu signals cells to build the structural support of tissue.
Dermal-Cell Research Models
Investigation into dermal fibroblast proliferation and keratinocyte function.
Simple explanation: Evaluating how GHK-Cu interacts with the primary cells responsible for dermal-cell behavior in laboratory models.
In vitro and Preclinical Tissue-Model Research
Analysis of metalloproteinase modulation during the inflammatory phase of repair.
Simple explanation: Looking at how GHK-Cu manages the cleanup and reconstruction phases of injury models.
Oxidative Stress & Protection
Research into lipid peroxidation and antioxidant enzyme levels (SOD).
Simple explanation: Studying GHK-Cu's role in oxidative-stress response markers in controlled models.
03
Research Highlights & Focus Areas
- 01
Collagen-Related Pathways and Extracellular Matrix Modeling
Examined in dermal fibroblast models for upregulation of collagen types I and III and glycosaminoglycan synthesis โ the core structural outputs of the extracellular matrix.
- 02
Dermal-Cell Research Models
Investigated across skin models for effects on fibroblast proliferation, keratinocyte function, and the organization of dermal fibers in controlled laboratory settings.
- 03
In Vitro and Preclinical Tissue-Model Research
Used in tissue-culture and preclinical models to study metalloproteinase modulation and the balance between matrix breakdown and reconstruction during the repair process.
- 04
Oxidative Stress and Cellular Protection Pathways
Studied for its relationship to lipid peroxidation markers and antioxidant enzyme activity, including superoxide dismutase (SOD), in oxidative-stress research models.
- 05
Gene Expression and Biological Signaling Systems
Profiled in gene-expression studies reporting broad modulation of genes associated with tissue remodeling, stress response, and cellular signaling systems.
04
Compliance & Protocol
Key handling, storage, and research-use protocols summarized for qualified laboratory professionals. Full batch documentation and certificates of analysis ship with every order.
What This Product Is Not
- Not a medication or pharmaceutical
- Not a dietary supplement
- Not a cosmetic or skincare product
- Not a medical treatment
- Not a diagnostic tool
- NOT for human or animal consumption
Handling & Storage
Store at -20ยฐC. Keep container tightly closed in a dry and well-ventilated place. Light sensitive.
First-Aid Measures
- Inhalation:
- Move to fresh air. If not breathing, give artificial respiration.
- Skin contact:
- Wash off with soap and plenty of water.
- Eye contact:
- Flush eyes with water as a precaution.
Research Use Only
Sold strictly for laboratory research and in vitro testing. Any other use is prohibited. The purchaser assumes full responsibility for compliance with applicable laws and regulations.
Disposal & Environmental Notes
Dispose of unused material and containers in accordance with local, state, and federal regulations for research chemicals. Avoid environmental release.
Add GHK-Cu to your procurement list
$89.00 USD ยท Matrix Biology Research ยท For laboratory research only.